Tamás Korcsmáros
I am working on networks of signal transduction pathways in collaboration with Péter Csermely (Semmelweis University, LINK-group), Tibor Vellai (Eötvös University, Dept. of Genetics), Tamás Vicsek and
Bálint Szabó (Eötvös University, Dept. of Biological Physics). Our aim is to experimentally prove our hypothesis on embed adaptation of network topology in C. elegans. I have built a universal signaling pathway network and I will
perform physiological experiments based on the network analysis. I am working with four research students:
- Lilian Zsákai, biology student, doing bioinformatics and signaling network building
- Petra Rovó, chemistry student, doing genetic experiments on C. elegans
- Zoltán Spiró, biology student, doing biochemical works and
- Dávid Fazekas, biology student, doing videomicroscopical movement analysis on C. elegans.
Personal
- Place and date of birth: Budapest, 8th, October, 1982.
- Nationality: Hungarian
- Address: Sip street 16-18. Budapest, Hungary, H-1075
- Phone: +361-32-12-378, +3630-268-6590
- E-mail: korcsmaros [at] linkgroup.hu
Education
- 1997-2002: Secondary School of the Kürt Foundation
- 2002-2007: Eötvös Loránd University of Science, Budapest, Faculty of Biology
- 2005-2007: Specialization: Molecular Biology and Biochemistry
Research and Professional Experience
- 2001- Research Associate, Semmelweis Univ. Dept. Med. Chem.
- 2001-2004: Chaperone group: Redox adaptation in diabetes and in alfa-1-antitrypsin deficient transgenic mice
- 2005- Link group: Robustness and adaptation of the signaling network in C. elegans
Honors and Awards
- 2001 2nd National Competition for Research Students: Biochemistry
section: 1st place
- 2002 Hungarian Innovative and Scientific Competition: Commendatory place
- 2003 National Competition for University Research Students in Biology:
Junior award
- 2004 Research Student Conference of the Semmelweis Medical University:
3rd place
- 2004 3rd National Competition for Research Students: Biology section:
3rd place
- 2005 Dean's Award of the Faculty of Science (ELTE) for outstanding
organizational work for the Biologists' Research Student Movement
- 2007 Research Student Conference of the Semmelweis Medical University:
Commendatory place
Organizational Experiences:
- 2001-2005: Vice president, president and managing president of the Hungarian Research Student Association
- 2002- Vice president of the Charity Commissioners of the Research Student Foundation
- 2004-2007: Student President of the Biology Research Student Movement at the Eötvös Loránd University of Science
- 2005-2007: Organizer of the Old Research Student Movement
- 2003-2005: Secretary of the Organizing Committee of the 9th IUBMB Conference & 30th FEBS Congress held in Budapest, Hungary 2005
- 2005-2007: Secretary of the Organizing Committee of the World Conference of Stress, Budapest, Hungary 2007
- 2005- Vice president of the Hungarian Cell Stress Society
- 2006- Director of the Predinet Ltd.
- 2007-2010: Student secretary of the Research Student Council of the
Faculty of Science, Eötvös University
- 2007- Chairman of the Foundation for Old Research Students
Publication
Publications on research topics:
- Csermely, P., Korcsmáros, T., Kovács, I.A., Szalay M.S. and Sõti, C. (2008) Systems biology of molecular chaperone networks. In: The biology of extracellular molecular chaperones. Novartis Foundation Symposium Series Vol. 291, Wiley, pp. 45-58. Download it!

- Nardai G., Korcsmaros, T. and Csermely, P. (2002) Reduction of the endoplasmic reticulum accompanies the oxidative damage of diabetes mellitus, In: Redox regulation (eds.: A. Pompella, G. Banhegyi and M. Wellman-Rousseau), NATO Science Series, I/347, 281-289.
- Nardai G., Korcsmaros, T., Papp, E. and Csermely, P. (2003) Reduction of the endoplasmic reticulum accompanies the oxidative damage of diabetes mellitus. Biofactors 17, 259-267.IF: 1,7
- Papp, E., Korcsmaros, T., Nardai G., and Csermely, P. (2004) Changes of cellular redox homeostasis and protein folding in diabetes, In: Cellular dysfunction in atherosclerosis and diabetes - Reports from bench to bedside (eds.: M. Simionescu, A. Sima, D. Popov), Plenum Press, 228-235.
- Nardai G., Stadler, K., Papp, E., Korcsmaros, T. Jakus, J., and Csermely, P. (2005) Diabetic changes in the redox status of the microsomal protein folding machinery. Biochemical and Biophysical Research Communications 334, 787-795. IF: 2,9
- Nardai, G., Papp, E., Korcsmaros, T., Stadler, K., Jakus, J. and Csermely, P. (2005) Possible links between metabolism and oxidative protein folding. Conseqences of a diabetes study, In: Redox regulation (eds.: A. Pompella, G. Banhegyi and M. Wellman-Rousseau), NATO Science Series, vol. 363, 101-109.
- Papp, E., Nardai, G., Sreedhar, A.S., Korcsmaros, T. and Csermely, P. (2005) Effects of unfolded protein accumulation on the redox state of the endoplasmic reticulum, In: Redox regulation (eds.: A. Pompella, G. Banhegyi and M. Wellman-Rousseau), NATO Science Series, vol. 111-119.
- Papp E., Szaraz P., Korcsmaros T. and Csermely, P. (2006) Changes of
endoplasmic reticulum chaperone complexes, redox state, and impaired
protein disulfide reductase activity in misfolding alfa-1-antitrypsin
transgenic mice.
FASEB Journal 20 (7): 1018-20. IF: 6.8
- Korcsmaros, T., Kovacs, I. A., Szalay, M. S. and Csermely, P (2006)
Molecular chaperones: The modular evolution of cellular networks.
Journal of Bioscience 32 (3): 441-446. IF: 1,5
- Szalay, M., Kovács, I.A., Korcsmáros, T., Böde. C. and Csermely, P. (2007) Stress-induced rearrangements of cellular networks: consequences
for protection and drug design. FEBS Lett. (in press) IF: 3,5
- Böde, C., Kovacs, I.A., Szalay M., Palotai, R., Korcsmaros, T. and
Csermely, P. (2007) Network analysis of protein dynamics. FEBS Lett. (in
press) IF: 3,5
- Korcsmáros, T., Szalay, M., Böde. C., Kovács, I.A., and Csermely, P.
(2007) How to design multi-target drugs: Target-search options in
cellular networks. Exp. Op. Drug Discovery (in press)
Publications on talent recruitment
- Csermely, P., Borsodi, Z., Korcsmáros, T. és Pató, B. (2002) Six Years of Scientific Research Training in Hungary. Progress, Plans, Problems. In: Science Education: Talent Recruitment and Public Understanding, (Csermely, P. and Lederman, L. eds.) NATO Science Series, vol. V/38. pp. 191-198., IOS Press
- Csermely P., Amrein K., Borsodi Z., Korcsmar P., Korcsmáros T.,Pato B. and Tomor K. (2002) 5th National Conference of high school researchers (in Hungarian). Természet Világa 133, IX-XI
- Borsodi Z., Csermely P., Korcsmáros T. and Pato B. (2002) Research Opportunities for high school students (in Hungarian) Magyar Felsőoktatás, 12-13.
- Borsodi Z., Csermely P., Korcsmáros T. and Pato B. (2002) Research Opportunities for high school students (in Hungarian) Magyar Tudomány, 108, 673-676.
- Csermely P., Borsodi Z., Korcsmáros T. and Pato B. (2002) Gifted students in high school and in university, plenary presentation, Hungarian Teacher Conference
- Csermely, P., Korcsmáros, T. és Lederman, L. (eds., 2005) Science Education: Best Practices of Research Training for Students under 21, NATO Science Series, V/47. IOS Press, 235 pages.
- Sulyok K., Soter A., Minarik F., Szalay M., Fazekeas L., Korcsmáros T. (2005) Nationwide mentorship network for talented high school students in Hungary. In: Science Education: Best Practices of Research Training for Students under 21, NATO Science Series, V/47., pp. 186-190., IOS Press
- Böde, C. and Korcsmáros T. (2006) eKut, the Next Step for old high
school research students. In: Csermely, P., Korlevic, K. and Sulyok, K.
(eds.) Science Education: Models and Networking of Student Research
Training under 21, NATO Security through Science Series, Human and Societal Dynamics E, V/16., pp. 55-58., IOS Press
Memberships, Societies:
- Hungarian Biological Society, Section of Animal Biology
- Hungarian Biochemical Society, Section of Molecular Biology
- Hungarian Cell Stress Society
- Hungarian Research Student Association
- Durrell Wildlife Conservation Trust
- Dian Fossey Gorilla Fund